The blood vessels respond by wanting to start the healing up process. The cells of the bloodstream vessel walls release chemicals that cause the surface of the walls to become very sticky. After this process begins, other things such as calcium, proteins and inflammatory cells began to stick to the bloodstream vessel walls as they pass through. The extra fat along with the rest that ends up sticking to the walls is called plaque. The plaque gets thicker and thicker and eventually causes the arteries to harden, which is known as atherosclerosis. The deposits of plaque are hard externally but have a soft, mushy consistency to the interior.Researchers also remember that some of the areas of the brain which were activated when participants experienced a worsening of chronic discomfort have been shown to be associated with other styles of pain found in other studies. However, researchers also noticed activation of some areas, including the superior parietal lobule, which have been less associated with pain in previous research frequently. ‘While this study begins to discover some of the basic physiology of the mind since it processes pain, more studies are had a need to help us know how the brain function may change during the period of treatment of discomfort and to examine the mind mechanisms by which pain improves,’ Wasan stated. ‘We are getting nearer to describing, on an objective level, the way the body and human brain are reacting when a patient reports having more pain.