Causes and Treatment of Mesothelioma Mesothelioma is a form of lung cancer, predominantly caused by contact with asbestos fibers inability to gain erection . Actually, mesothelioma is a cancer of the mesothelium, the sheath that covers major organs such as the lungs , the heart and the stomach cavity . Pleural mesothelioma is by considerably the most common kind. Mesothelioma and Asbestos When asbestos fibers are inhaled, they become embedded in the lining of the lungs. Due to their small needle-like size, the normal defenses of the physical body are unable to detect them.