He feeds Carol, and puts on her behalf makeup even. She was diagnosed with Alzheimer’s disease seven years ago. Alzheimer’s and the silver tsunami: Is America prepared? Carol’s memory was slipping when LaPook 1st met them in 2008. At the right time, Carol could understand that she was 65 years old. Right now, Carol said, ‘How old am I? 80? No? I have no idea.’ Mike was feeling any risk of strain in 2008. ‘It’s hard to cope with,’ he said. 3 years later on, he’s gained 15 pounds and takes medicines for anxiety and sleep. He understands he should workout but cannot find the time. Video: Role of caregivers Mike is among the nearly 15 million Americans offering 17 billion hours of unpaid Alzheimer’s treatment a 12 months.Further, they discovered that these activating ncRNAs can attach to Mediator at multiple places within the Mediator proteins complicated, and Mediator itself can interact with the enhancer component site on DNA that encodes these activating ncRNAs. Their results also identified how mutations in a protein that makes up the Mediator complicated, called MED12, drastically diminishes Mediator's ability to associate with activating ncRNAs. Mutations in the MED12 protein certainly are a marker for FG syndrome , a uncommon genetic disorder that leads to abnormalities throughout the body and varying levels of physical and neurological complications.